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HomeWorld54-year-old woman, who received pig kidney transplant plus a heart pump, dies

54-year-old woman, who received pig kidney transplant plus a heart pump, dies



Lisa PisanoA 54-year-old New Jersey woman died Sunday after surviving on one kidney for 47 days. genetically modified pigShe was the second person to receive such a transplant and was seriously ill, with both her kidneys and heart failing.
Pisano’s transplant took place on April 12, just eight days after receiving a mechanical heart pump.
due to inadequate blood flow associated with the heart pump, Pig kidney The kidney was damaged, and surgeons had to remove it on May 29. After the transplant, Pisano resumed kidney dialysis, but was eventually transferred to hospice care. Her case was unique, as she was the first person with a heart pump to also receive a heart pump. Organ transplantBecause patients with kidney failure are usually ineligible for a heart pump due to the high risk of death.
Dr. Robert Montgomery, director of the NYU Langone Transplant Institute, praised Pisano's contributions to the field of xenotransplantation, saying, “Lisa's contributions to the fields of medicine, surgery and technology are admirable.” Xenotransplantation His bravery cannot be praised enough. His courage has given hope to thousands of people suffering from end-stage kidney or heart failure who may soon benefit from an alternative supply of organs.”
Pisano's case follows that of Richard Slayman, 62, who was the first patient to receive a kidney from a genetically engineered pig in March at Mass General Brigham in Boston. Although Slayman was healthy enough to be discharged two weeks after the surgery, like Pisano, he had complex medical problems and died within two months.
Xenotransplantation has made significant progress in recent years, but the procedures remain experimental. Animal organs are only allowed for patients who are too sick to receive human organs and risk dying without treatment.
Biotech companies are attempting to address the dire shortage of transplant organs in the United States, where more than 100,000 individuals, primarily needing kidneys, are on waiting lists. Tragically, many die before receiving a transplant. These companies are focusing on genetic modifications in pigs, with the aim of creating organs that more closely resemble human organs and reduce the likelihood of rejection by the recipient's immune system.



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